Is this chainring compatible with Shimano 11-speed chain?

Yes — the FC-R7000 39T is designed exclusively for 11-speed road chains. Using a 10-speed chain will result in poor shifting and potential chain drop.

Can I mix this Shimano 39T inner ring with a non-Shimano 53T outer ring?

Technically possible but not recommended. Shimano's ramp-and-pin geometry is calibrated to work with matching Shimano chainrings. Mixed brand rings can cause hesitant or slow front shifts.

Shimano

Shimano 105 Chainring 39T for FC-R7000 (Black)

Name: Shimano 105 Chainring 39T for FC-R7000 (Black)
Brand: Shimano
SKU: Y1WV39000
Price: 1040.00 INR
Availability: InStock
Author: InstaSport Editorial

₹1040.00

Description

FEATURES Front chainring type: DoubleChainring 39T-MW (for 53-39T, Black) COMPATIBLE MODEL FC-R7000 COMPATIBLE SERIES SHIMANO 105 R7000 Series MODEL NO WP-Y1WV39000 SERIES SHIMANO 105 R7000 Series Chain Ring Type 39T Speed 11-speed